GENETICS - BIOLOGY 97 - Homework due November 3, 2009

In preparation for the next unit of study, the following must be done prior to class on Tuesday, Nov.  3.

Part I.  You must draw these by hand - do NOT copy- paste or trace.  The drawings for 1-3 must be molecular representations, with each atom identified by letter.

1.  Draw each of the 4 nucleotides commonly found in DNA, and each of the 4 commonly found in RNA.  Draw at least one as a nucleoside monophosphate, one as a nucleoside diphosphate, and one as a nucleoside triphosphate in each group.  Although you will not be asked to draw the 4 bases on an exam or closed book quiz, you must do it here - this is “open book”.

2.  Draw double-stranded DNA (dsDNA) in which the first strand is T-C-G-A.

3.  Draw the RNA which would be transcribed from that DNA.

4.  If the following represents a fragment of a transcript (that is, we need not expect any regulatory elements or signals), write the DNA from which it was transcribed.  Be sure that the DNA is oriented correctly.

5' ...- A-U-G-U-U-U-G-C-A-A-G-G-G-U-U-A-U-G-C-C-A-U-A-A-C-G-A-G-G-C-C-C-A-U- ... 3'


5.  Using the genetic code decoder information in your text, translate the following messages.  
a.  5' ...- A-U-G-U-U-U-G-C-A-A-G-G-G-U-U-A-U-G-C-C-A-U-A-A-C-G-A-G-G-C-C-C-A-U- ... 3'





b.  5' ...- A-C-U-U-C-C-U-C-A-U-G-U-G-U-C-A-U-G-C-C-G-U-C-A-C-U-G-U-G-A-C-C-U-U- ... 3'




 
    c.  Which one might actually represent a usable coding sequence, and why?



Part II.  Not to hand in:

1.  copy the drawing of replication
2.  copy the drawing of translation initiation
3.  copy the drawing of translation elongation